Welcome to the Protein Link Explorer (PLEX). Given an amino acid sequence or its GenBank sequence identifier, PLEX allows a phylogenetic profile to be constructed, which can subsequently be compared to profiles of upto 350,111 other proteins from 89 fully sequenced genomes, that are stored in our database. In addition, PLEX can accept sophisticated phylogenetic profile inputs and comparison parameters, including individual organism or group-based profiles. Gene neighbors and rosetta stone links of all proteins that match the query profile can also be investigated.

To start using PLEX, click on the 'Submit a new job' button (PLEX treats each individual query as a new job). The user is assigned a job ID, which can be used to retrieve results for a period of 24hrs from the time the job was submitted. If you have submitted a job previously, you can retrieve it by clicking on the 'Retrieve a previously submitted job' button. This version of PLEX is version 2.4.


Submit a new job Retrieve a previously submitted job


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References:

Citing PLEX:
  • Date, S. V & Marcotte, E. M.  Protein function prediction using the Protein Link Explorer (PLEX). (to appear in Bioinformatics).
    (See the advance online publication)
PLEX acknowledges a number of publications, listed here.

Copyright © 2002 - 2005, Shailesh Date and Edward Marcotte. The protein link explorer data and server is the property of the University of Texas, and cannot be used for commercial purposes without written permission of Edward Marcotte and the University of Texas. It is forbidden to redistribute, derivatize, or encapsulate the protein link explorer data or server in another database without permission. Sale of information derived from it, whether directly or in revised form, is forbidden except by permission of the University of Texas and Edward Marcotte. All copies or mirrors of the protein link explorer must carry this notice.